Primary Literature
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- Xu Z, et al. (2023) Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun 14(1):5849 PMID: 37730685
- Deegan TD, et al. (2020) CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold. Elife 9 PMID: 32804080
- Liu L, et al. (2020) Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks. Cell Mol Life Sci 77(15):3041-3058 PMID: 31728581
- Langston LD, et al. (2017) Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks. Elife 6 PMID: 28869037
- Perez-Arnaiz P, et al. (2017) An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7. Nucleic Acids Res 45(12):7261-7275 PMID: 28510759
- Zhou JC, et al. (2017) CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome. Proc Natl Acad Sci U S A 114(16):4141-4146 PMID: 28373564
- Perez-Arnaiz P and Kaplan DL (2016) An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation. J Mol Biol 428(23):4608-4625 PMID: 27751725
- Herrera MC, et al. (2015) A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase. Nucleic Acids Res 43(21):10238-50 PMID: 26338774
- Maculins T, et al. (2015) Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase. Curr Biol 25(17):2254-9 PMID: 26255844
- Sun J, et al. (2015) The architecture of a eukaryotic replisome. Nat Struct Mol Biol 22(12):976-82 PMID: 26524492
- Langston LD, et al. (2014) CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication. Proc Natl Acad Sci U S A 111(43):15390-5 PMID: 25313033
- Maric M, et al. (2014) Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication. Science 346(6208):1253596 PMID: 25342810
- Bruck I and Kaplan DL (2013) Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress. J Biol Chem 288(11):7550-7563 PMID: 23382391
- Watase G, et al. (2012) Mcm10 plays a role in functioning of the eukaryotic replicative DNA helicase, Cdc45-Mcm-GINS. Curr Biol 22(4):343-9 PMID: 22285032
- Bruck I and Kaplan DL (2011) GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding. J Biol Chem 286(16):14157-67 PMID: 21362622
- Lydeard JR, et al. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev 24(11):1133-44 PMID: 20516198
- Tseng SF, et al. (2008) Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast. PLoS Genet 4(4):e1000060 PMID: 18437220
- Asturias FJ, et al. (2006) Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy. Nat Struct Mol Biol 13(1):35-43 PMID: 16369485
- Kanemaki M, et al. (2003) Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo. Nature 423(6941):720-4 PMID: 12768207
- Takayama Y, et al. (2003) GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev 17(9):1153-65 PMID: 12730134
- Tsubota T, et al. (2003) Double-stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase epsilon and of the Dpb3p-Dpb4p subassembly. Genes Cells 8(11):873-88 PMID: 14622139
- Zou L and Stillman B (2000) Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Mol Cell Biol 20(9):3086-96 PMID: 10757793
- Zou L and Stillman B (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280(5363):593-6 PMID: 9554851
- Aparicio OM, et al. (1997) Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell 91(1):59-69 PMID: 9335335