Gene Ontology Help

REG2-GLC7 phosphatase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Protein phosphatase complex with a role in theresponse to glucose levels. During steady-state growth in high glucose, the SNF1 kinase complex (CPX-232/CPX-2800/CPX-231) is inactive and REG2 is not expressed. Prolonged glucose starvation leads to SNF1-dependent accumulation of REG2. Once glucose becomes abundant, REG2-GLC7 contributes to the rapid dephosphorylation and inactivation of SNF1 which acts as a central regulator of cellular energy homeostasis.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

hydrolase activity, phosphatase activity, biological process