Gene Ontology Help

CDC24-FAR1-Gbetagamma complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Required for oriented growth of haploid cells in response to a pheromone gradient created by a mating partner of the opposite mating type. Forms at the cell cortex during mating, when a Far1-Cdc24 complex translocates from the nucleus. Recruits Cdc42 (P19073) and Bem1 (P29366) away from the bud site, thus providing the switch from bud growth to polarized growth, enabling the cell to project a shmoo towards the source of a pheromone gradient, and thus grow towards the mating partner. Binding to Gbetagamma may trigger a conformational change in Far1 that is required for its ability to activate Cdc24.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

biological process, cell cortex, cytoplasm