Primary Literature
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- Li QX, et al. (2022) Kae1 of Saccharomyces cerevisiae KEOPS complex possesses ADP/GDP nucleotidase activity. Biochem J 479(23):2433-2447 PMID: 36416748
- Li R and Deed RC (2021) Reciprocal hemizygosity analysis reveals that the Saccharomyces cerevisiae CGI121 gene affects lag time duration in synthetic grape must. G3 (Bethesda) 11(4) PMID: 33681985
- He MH, et al. (2019) KEOPS complex promotes homologous recombination via DNA resection. Nucleic Acids Res 47(11):5684-5697 PMID: 30937455
- Liu YY, et al. (2018) Yeast KEOPS complex regulates telomere length independently of its t<sup>6</sup>A modification function. J Genet Genomics 45(5):247-257 PMID: 29804714
- Edvardson S, et al. (2017) tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy. Eur J Hum Genet 25(5):545-551 PMID: 28272532
- Wan LC, et al. (2017) Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. Nucleic Acids Res 45(2):805-817 PMID: 27903914
- Wan LC, et al. (2016) Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis. Nucleic Acids Res 44(14):6971-80 PMID: 27302132
- Dzikowska A, et al. (2015) KAEA (SUDPRO), a member of the ubiquitous KEOPS/EKC protein complex, regulates the arginine catabolic pathway and the expression of several other genes in Aspergillus nidulans. Gene 573(2):310-20 PMID: 26210809
- Peng J, et al. (2015) Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity. PLoS Genet 11(3):e1005071 PMID: 25822194
- Zhang W, et al. (2015) Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex. Nucleic Acids Res 43(6):3358-72 PMID: 25735745
- Thiaville PC, et al. (2014) Cross kingdom functional conservation of the core universally conserved threonylcarbamoyladenosine tRNA synthesis enzymes. Eukaryot Cell 13(9):1222-31 PMID: 25038083
- Hu Y, et al. (2013) Telomerase-null survivor screening identifies novel telomere recombination regulators. PLoS Genet 9(1):e1003208 PMID: 23390378
- Perrochia L, et al. (2013) Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification. Nucleic Acids Res 41(20):9484-99 PMID: 23945934
- Perrochia L, et al. (2013) In vitro biosynthesis of a universal t6A tRNA modification in Archaea and Eukarya. Nucleic Acids Res 41(3):1953-64 PMID: 23258706
- Rojas-BenÃtez D, et al. (2013) The Drosophila EKC/KEOPS complex: roles in protein synthesis homeostasis and animal growth. Fly (Austin) 7(3):168-72 PMID: 23823807
- Wan LC, et al. (2013) Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res 41(12):6332-46 PMID: 23620299
- Costessi A, et al. (2012) The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. PLoS One 7(8):e42822 PMID: 22912744
- Daugeron MC, et al. (2011) Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs. Nucleic Acids Res 39(14):6148-60 PMID: 21459853
- Kato Y, et al. (2011) Cell polarity in Saccharomyces cerevisiae depends on proper localization of the Bud9 landmark protein by the EKC/KEOPS complex. Genetics 188(4):871-82 PMID: 21625000
- Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81 PMID: 21183954
- Hecker A, et al. (2009) The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya. Biochem Soc Trans 37(Pt 1):29-35 PMID: 19143597
- Hecker A, et al. (2008) Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex. EMBO J 27(17):2340-51 PMID: 19172740
- Mao DY, et al. (2008) Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine. Mol Cell 32(2):259-75 PMID: 18951093
- Peggion C, et al. (2008) Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily. FEBS J 275(23):5919-33 PMID: 19021767
- Hecker A, et al. (2007) An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro. Nucleic Acids Res 35(18):6042-51 PMID: 17766251
- Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68 PMID: 16564010
- Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 PMID: 16874308