NPR2 / YEL062W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant shows abnormal localization of Tor1p and increased phosphorylation of Sch9p; null mutation results in defective autophagy and lower utilization of proline, ammonium or urea as nitrogen source; null mutant is resistant to cisplatin and doxorubicin; homozygous null mutant diploid has defects in meiosis and sporulation; in systematic studies null mutant is sensitive to azole drugs, tunicamycin, DTT, camptothecin, but resistant to bleomycin and caffeine

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources