SWI3 / YJL176C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

SWI3/YJL176C is a non-essential gene; null mutants are viable and exhibit a range of phenotypic effects, including decreased alkaline pH resistance, chronological lifespan, desiccation resistance, endocytosis, gamma ray resistance, hyperosmotic stress resistance, metal resistance, mitotic recombination, peroxisomal transport, resistance to enzymatic treatment, respiratory growth, toxin resistance, transposable element transposition, and utilization of carbon, iron, and phosphorus sources. Null mutants also show delayed cell cycle progression in the G1 phase, abnormal vacuolar morphology, increased heat sensitivity, absent sporulation, and decreased vegetative growth. Reduction of function mutants exhibit decreased alkaline pH resistance, heat sensitivity, metal resistance, and respiratory growth, but increased osmotic stress resistance and vegetative growth. Overexpression of SWI3/YJL176C results in decreased vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources