SNF7 / YLR025W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

SNF7/YLR025W is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including decreased acid pH resistance, increased biofilm formation, abnormal chemical compound accumulation, increased chemical compound excretion, decreased chronological lifespan, abnormal colony appearance, decreased competitive fitness, decreased desiccation resistance, decreased endocytosis, increased heat sensitivity, decreased hyperosmotic stress resistance, altered metal resistance, increased nutrient utilization, decreased oxidative stress resistance, decreased replicative lifespan, altered resistance to chemicals, decreased respiratory growth rate, decreased sporulation efficiency, decreased telomere length, decreased toxin resistance, decreased transposable element transposition, decreased utilization rates of carbon and nitrogen sources, abnormal vacuolar morphology, decreased vegetative growth rate, decreased acquired thermotolerance, decreased protein secretion, increased protein/peptide accumulation, abnormal protein/peptide distribution and modification, decreased RNA accumulation, and absent vacuolar transport. Reduction of function mutants exhibit abnormal vacuolar transport, while activation mutants show abnormal lipid particle morphology. Overexpression of SNF7 results in decreased vegetative growth, abnormal actin cytoskeleton morphology, increased protein/peptide accumulation, and increased replicative lifespan.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources