Primary Literature
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- Johnson DL, et al. (2024) Ccr4-not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy. J Biol Chem 300(8):107582 PMID: 39025453
- Pfannenstein J, et al. (2024) Characterization of BioID tagging systems in budding yeast and exploring the interactome of the Ccr4-Not complex. G3 (Bethesda) 14(11) PMID: 39271111
- Allen G, et al. (2023) Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events. Genome Biol 24(1):30 PMID: 36803582
- Chen S, et al. (2023) Not4-dependent targeting of MMF1 mRNA to mitochondria limits its expression via ribosome pausing, Egd1 ubiquitination, Caf130, no-go-decay and autophagy. Nucleic Acids Res 51(10):5022-5039 PMID: 37094076
- Yin Z, et al. (2023) Bidirectional roles of the Ccr4-Not complex in regulating autophagy before and after nitrogen starvation. Autophagy 19(2):415-425 PMID: 35167422
- Nahar A, et al. (2022) Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones. Cell Rep 39(10):110918 PMID: 35675778
- Bhagwat M, et al. (2021) Replication stress inhibits synthesis of histone mRNAs in yeast by removing Spt10p and Spt21p from the histone promoters. J Biol Chem 297(5):101246 PMID: 34582893
- Fujii S, et al. (2021) Pan2-Pan3 complex, together with Ccr4-Not complex, has a role in the cell growth on non-fermentable carbon sources. Biochem Biophys Res Commun 570:125-130 PMID: 34280615
- Silva E, et al. (2020) Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response. G3 (Bethesda) 10(9):2981-2988 PMID: 32732306
- Hosoyamada S, et al. (2019) The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts. Mol Cell Biol 40(1) PMID: 31611247
- Sachdev R, et al. (2019) Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA. Elife 8 PMID: 30648970
- Chou WL, et al. (2017) Novel interaction between CCR4 and CAF1 in rice CCR4-NOT deadenylase complex. Plant Mol Biol 93(1-2):79-96 PMID: 27714489
- Gupta I, et al. (2016) Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex. Cell Rep 15(8):1782-94 PMID: 27184853
- Mugler CF, et al. (2016) ATPase activity of the DEAD-box protein Dhh1 controls processing body formation. Elife 5 PMID: 27692063
- Makino S, et al. (2015) Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast. J Biol Chem 290(13):8331-47 PMID: 25657010
- Kruk JA, et al. (2011) The multifunctional Ccr4-Not complex directly promotes transcription elongation. Genes Dev 25(6):581-93 PMID: 21406554
- Nasertorabi F, et al. (2011) Insights into the structure of the CCR4-NOT complex by electron microscopy. FEBS Lett 585(14):2182-6 PMID: 21669201
- Lee D, et al. (2010) PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure. J Mol Biol 399(4):562-75 PMID: 20435044
- Cui Y, et al. (2008) Genome wide expression analysis of the CCR4-NOT complex indicates that it consists of three modules with the NOT module controlling SAGA-responsive genes. Mol Genet Genomics 279(4):323-37 PMID: 18214544
- Gallo CM, et al. (2008) Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos. Dev Biol 323(1):76-87 PMID: 18692039
- Morita M, et al. (2007) Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol Cell Biol 27(13):4980-90 PMID: 17452450
- Ohn T, et al. (2007) CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4. Nucleic Acids Res 35(9):3002-15 PMID: 17439972
- Mulder KW, et al. (2005) DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. Nucleic Acids Res 33(19):6384-92 PMID: 16275785
- Clark LB, et al. (2004) Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity. J Biol Chem 279(14):13616-23 PMID: 14734555
- Collart MA and Timmers HT (2004) The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways? Prog Nucleic Acid Res Mol Biol 77:289-322 PMID: 15196896
- Qiu H, et al. (2004) An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p. Mol Cell Biol 24(10):4104-17 PMID: 15121833
- Temme C, et al. (2004) A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila. EMBO J 23(14):2862-71 PMID: 15215893
- Viswanathan P, et al. (2004) Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal. J Biol Chem 279(23):23988-95 PMID: 15044470
- Westmoreland TJ, et al. (2004) Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae. Eukaryot Cell 3(2):430-46 PMID: 15075273
- Morel AP, et al. (2003) BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms. J Cell Sci 116(Pt 14):2929-36 PMID: 12771185
- Swanson MJ, et al. (2003) A multiplicity of coactivators is required by Gcn4p at individual promoters in vivo. Mol Cell Biol 23(8):2800-20 PMID: 12665580
- Westmoreland TJ, et al. (2003) Dhh1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression in yeast. J Surg Res 113(1):62-73 PMID: 12943812
- Chen J, et al. (2002) CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. EMBO J 21(6):1414-26 PMID: 11889047
- Russell P, et al. (2002) Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex. J Mol Biol 322(1):27-39 PMID: 12215412
- Tucker M, et al. (2002) Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J 21(6):1427-36 PMID: 11889048
- Chen J, et al. (2001) Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. J Mol Biol 314(4):683-94 PMID: 11733989
- Denis CL, et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34 PMID: 11404327
- Dupressoir A, et al. (2001) Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding. BMC Genomics 2:9 PMID: 11747467
- Liu HY, et al. (2001) Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J Biol Chem 276(10):7541-8 PMID: 11113136
- Badarinarayana V, et al. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54 PMID: 10880468
- Maillet L, et al. (2000) The essential function of Not1 lies within the Ccr4-Not complex. J Mol Biol 303(2):131-43 PMID: 11023781
- Bai Y, et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51 PMID: 10490603